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10,11 Curcumin Preclinical and in vitro data suggest that curcumin can inhibit DPP-4 activity and enhance glycemic control in diabetic animal models, potentially prolonging the active life of GLP-1, although this has not been confirmed in human mechanistic studies
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43.5% described at least one side effect
GLP-1 innovation is moving beyond obesity Drug developers are racing to expand indications to assume market dominance
Specifically, LEAP2 acts both as a GHSR antagonist and an inverse agonist, thereby blocking the effects of ghrelin and suppressing the constitutive activity of the receptor [23, 28]
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