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If side effects persist and remain intolerable despite extended up-titration, a lower maintenance dose may be considered to support adherence and reduce the risk of treatment discontinuation [66]
The encouraging news is that these symptoms are typically temporary and can be managed with a few simple lifestyle adjustments
Always follow your doctors advice
This tolerability advantage becomes increasingly important for long-term treatment adherence
Aronne notes that diabetes is also a leading cause of amputation
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