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One trial used 2000 g/day vitamin B 12 and demonstrated a mean difference of 680 pg/mL (95% confidence interval 392.7 to 967.3) in favor of oral vitamin B 12

When to Seek Medical Advice About B12 Levels Most individuals taking vitamin B12 supplements as directed do not require routine monitoring of serum levels unless they have specific medical conditions or are receiving treatment for documented deficiency

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