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Additionally, there are drug efflux pumps such as p -glycoprotein (P-gp), multidrug resistance associated protein (MRP) and drug metabolic enzymes, at the BBB to remove and/or inactivate small drug molecules from the brain [1]
Doesn't that solve the quality problem
Doi:10.1016/S0140-6736(21)00213-0 Wadden TA, Bailey TS, Billings LK, et al
Changes in blood sugar control If you have diabetes, you might notice: More stable blood sugar readings Lower fasting blood sugar levels Potentially a drop in your A1C beyond what semaglutide achieved For someone with an A1C of about 7% on semaglutide, tirzepatide might bring it closer to your target goal
All three have similar GI safety profiles (nausea 4045%)
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