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Finally, we identify current research gaps and propose future directions toward harnessing AST for promoting cognitive resilience and delaying the progression of neurodegenerative disorders

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In addition to oral l-carnitine, metformin was administered either intraperitoneally (ip, solubilized in 0.9% NaCl) at a concentration of 100 mg/kg of rat weight twice a day for 4 weeks in the l-carnitine + Metformin group [28]

doi: 10.1016/j.pediatrneurol.2020.09.009 83

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