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Patients on dupilumab or other biologics should continue their prescribed treatment and discuss any changes in eczema severity with their dermatologist rather than independently adjusting biologic dosing based on weight loss progress

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It was among the first synthetic GH secretagogues and played a central role in establishing that GH release could be stimulated independently of GHRH ultimately contributing to the discovery of the ghrelin receptor (GHS-R1a)