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After lipopolysaccharide/ Brucella abortus administration, the treatment of mice with olive extract (400 mg/kg p.o.) for 19 days significantly decreased immobility time and hyperalgesia along with an attenuation of oxidative stress (brain lipid peroxidation, reduced glutathione (GSH) levels, brain nitrite levels) and serum TNF- levels
In ferroptosis, free Fe2+ interacts with hydrogen peroxide to generate highly reactive lipid peroxides, resulting from the disruption of the balance between ferrous iron absorption, depletion and recycling (29)
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