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10.1038/s41380-020-0645-4 Mol Psychiatry
For example, preclinical experiments for eloralintide and petrelintide have reported favorable fat-versus-lean mass patterns
It slows gastric emptying, tempers the post-meal glucagon spike, and flips satiety switches in the hindbrain and hypothalamus
Supporting a diverse, healthy microbiome through prebiotic and probiotic-rich foods may therefore indirectly enhance GLP-1 activity, though evidence is still emerging
The 2024 FDA approval of resmetirom, the first targeted therapy for MASLD/MASH, represents a significant advancement (88)
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