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When an amylin analogue like cagrilintide is paired with a GLP-1/GIP receptor agonist, the complementary mechanisms appear to produce additive appetite suppression: cagrilintide slows gastric emptying through amylin receptor activation, while tirzepatide simultaneously boosts insulin secretion and reduces glucagon
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Outcomes observed in Phase 2 trials under carefully controlled conditions may differ from those seen in real-world clinical practice
Whilst gastrointestinal side effects such as nausea and diarrhoea are well documented, patients occasionally report changes in stool appearance, prompting questions about whether Ozempic causes dark stools
Open communication with your doctor is paramount for safe and effective semaglutide use
