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Tirzepatide acts on two gut-hormone pathways (GLP-1 and GIP) and is often associated with greater average weight loss, which is reflected in the pricing

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Image Credit: lucigerma / Shutterstock.com Introduction This article summarizes how oral glucagon-like peptide-1 (GLP-1) receptor agonists address weight-loss challenges, improve absorption, and enhance tolerability, as well as the promising future of GLP-1/glucose-dependent insulinotropic polypeptide (GIP) dual therapies

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for a given body weight, less muscle means more fat, and obesity is well-known to be a driver of insulin resistance and diabetes [71]