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GLP-1 also affects food intake, body weight, and has direct effects on the heart (52, 103)

The retatrutide versus tirzepatide dosage chart can help translate your current tirzepatide dose into an approximate retatrutide equivalent

2017 Apr 8;389(10077):1398 )

JAMA Internal Medicine, 182 (5), 513-519

However, in some patients, particularly those with pre-existing hypotension or taking antihypertensive medications, this could potentially contribute to orthostatic symptoms

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