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Patients should carefully consider the risks and benefits of bariatric surgery with their healthcare provider

Mechanistically, valproate may cause somnolence by inhibiting the reuptake of GABA (and thereby potentiating GABA signaling in the brain)

Med Care 42(12): 2004

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Comprehensive ePRO Portfolio: We have experience in supporting a wide range of ePRO measures to assess aspects of health important to patients with these diseases including: Health-related quality of life (HRQoL, e.g., SF-36, Impact of Weight on Quality of Life-Lite (IWQoL-Lite)(EQ-5D-5L), Food craving (e.g., Control of Eating Questionnaire (CoEQ)), Mental health (e.g., Columbia-Suicide Severity Rating Scale (C-SSRS), Patient Health Questionnaire-9 (PHQ-9)) and other measures such as the Patient Global Impression of Severity/Change (PCIS/C)