In patients in whom the major therapeutic goal is the compelling need to minimize the therapeutic risk pf hypoglycaemia, DPP-4 inhibitors are recommended as second line therapy after metformin failure at the same level as second line treatment options with GLP-1 receptor agonists, SGLT-2 inhibitors, or TZDs
[PubMed] [CrossRef] [Google Scholar] Esse R, Barroso M, Tavares de Almeida I, Castro R
Furthermore, high-dose L-carnitine significantly lowered the incidence of ventricular arrhythmias following myocardial infarction (Lango et al
rs2957692), which showed a positive correlation between CT-proET-1 and the incidence of type 2 diabetes (Sujana et al., 2022)
Springer Nature Lau J, et al