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The result at week 88: Continued tirzepatide: :Lost an additional 5.5% of body weight (total loss from baseline: ~25%) Switched to placebo: Regained 14.0% of body weight (net loss from baseline: ~9%) A 19-point swing between continued and discontinued groups

And the first big paper that talked about this was actually in Nature Medicine in 2003, and it was originally, I think I should credit Nigel Greig

Agrati C, Sacchi A, Bordoni V, Cimini E, Notari S, Grassi G, et al

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