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Why are the per-component loadings 5 mg instead of 10 mg

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At 26 weeks, mean percentage reductions in weight (the primary outcome) were 6.0 Percentage to 10.8 Percentage in the cagrilintide groups compared with 9.0 Percentage in the liraglutide group, and 3.0 Percentage with placebo [9]

Bacterial expression produces none of those and instead produces host-cell protein, host-cell DNA, endotoxin from the Gram- negative cell wall, species with incorrect or scrambled disulfide pairing, N-terminal heterogeneity from incomplete or over-enthusiastic processing of the initiator methionine and the leader region, methionine oxidation, deamidation, clipped forms generated by host proteases, and covalent or non-covalent aggregate

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