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RiskBenefit Assessment and Pharmacovigilance Needs Given the widespread use of GLP-1RAs and other incretin-based agents for obesity and T2D, comprehensive evaluation of even common GI adverse effects remains limited

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10.1152/ajpgi.1998.275.5.G984 68

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injections of 100 nmol kg 1 MK-801 ( n = 10), 100 nmol kg 1 GLP-1 ( n = 10), 100 nmol kg 1 GLP-1MK-801 ( n = 10) or vehicle (isotonic saline, n = 10) for 14 days

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In this context, Sample C exhibited the highest dispersibility value (92.74%), reflecting superior solubility performance

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