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In chemotherapy-sensitive patients, Keap1 (Kelch-like ECH-associated protein 1) binds to NRF2 and mediates NRF2 ubiquitination via the Cul3-E3 ligase complex, promoting its degradation and maintaining NRF2 at low levels [32]
Sterile, nonpyrogenic preparation for laboratory use
It is intended for use in studies involving metabolic flexibility and the quantification of energy substrate utilization within muscle tissue
Einstein (Sao Paulo)
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