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Opioid use may worsen gastric retention Higher prevalence of recent opioid use in the high RGC group Suggests an additive effect on gastric motility No difference in indication or duration of therapy Whether patients used GLP-1 RAs for diabetes or weight loss did not affect risk Duration of therapy was not a significant predictor Interpretation Withholding 7.5 days higher risk of retained gastric contents Fasting 21.3 hours strongest predictor of high RGC These thresholds optimize sensitivity and specificity for detecting risk
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The half-life of cagrilintide is 159-195 hours (approximately 6.6 to 8.1 days) making it suitable for once weekly subcutaneous administration [5]
The central case after price cuts and a modest volume response translates to about $36.5 billion
Increased insulin resistance due to alterations in normal DNA methylation How common is folate deficiency
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