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[1] [3] However, it is important to note that this concern relates specifically to medullary thyroid carcinoma, which arises from parafollicular C-cells, not the follicular cells affected in Graves disease
body composition shifts, when they happen, usually show up around weeks 8 to 12
In essence, GLP-1 effects provide safe and effective glucose control for diabetic patients and have achieved up to 20% weight loss in overweight and obese individuals, a milestone previously unseen with other therapeutic options
Genetic Predispositions and Personalized Dose Response: What You Should Know Recent research has identified genetic variants in GIPR pathway that correlate with differential responses to GLP-1 therapies
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![Physiologic effects of GLP-1 (adapted from Granata et al. [11])](https://www.researchgate.net/publication/359199250/figure/fig1/AS:11431281081130351@1661532031197/Physiologic-effects-of-GLP-1-adapted-from-Granata-et-al-11.png)
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