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The peptides naturally occurring status and well-characterized copper-binding properties have made it one of the most extensively studied bioactive tripeptides in dermatological research
Half-life can also be used to describe drug accumulation
GHK-Cu acts at the extracellular matrix (ECM) level, modulating the balance between matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) to regulate collagen turnover, and stimulating fibroblasts to produce collagen type I, collagen type III, and elastin
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