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doi:10.1056/NEJMoa1411892 6

[3] In vitro experiments indicate that Ipamorelin's interaction with the Growth Hormone Secretagogue Receptor type 1a (GHS-R1a) might influence the somatotroph cells located in the anterior segment of the pituitary gland

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There's also a theoretical interaction with Parkinson's medications like L-DOPAtyrosine might interfere with absorption or transport