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Vitiligo is a condition where the pigment producing cells, or melanocytes, are destroyed, leading to uneven skin pigmentation and white patches
This transgenic mouse overexpresses the human amyloid precursor protein (APP) carrying two familial AD mutations: The Swedish mutation (KM670/671NL), which increases total A production by enhancing -secretase cleavage, and the Indiana mutation (V717F), which alters -secretase cleavage to favor production of the more aggregation-prone amyloid-beta 142 peptide (A 142 ) [464467]
All removable parts should be taken out and washed with dish soap, while other parts can be thoroughly cleaned with all-purpose cleaner or disinfectant wipes
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doi: 10.1111/codi.15095 76 SunWDouRChenJLaiSZhangCRuanLet al
