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It's worth noting that the MHRA prescribing information for Mounjaro includes warnings about gallbladder and biliary tract events with GLP-1 receptor agonists

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Pros Cons No long-term safety data yet Gastrointestinal side effects are commonly reported May cause reactions at injection site Regular monitoring of kidney function is needed Anticipated Mounjaro side effects The safety and tolerability profile for tirzepatide is felt to be similar to other related diabetes medicines such as semaglutide and liraglutide