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SU = sulfonylurea a Ontario prices presented Source: Sponsors pharmacoeconomic submission 1 Results of the sponsors base case suggested an incremental cost of $3,355,258 in Year 1, $10,231,784 in Year 2, and $21,706,463 in Year 3, for a total incremental cost of $35,293,505 over the 3-year time horizon, when oral semaglutide is reimbursed as an adjunct to diet and exercise to improve glycemic control in adults with T2DM as monotherapy when metformin is considered inappropriate due to intolerance or contraindications or in combination with other medicinal products

Whitburn, J., Edwards, C

Its three-amino-acid structure (Lys-Pro-Val) allows it to resist proteolytic degradation in the gut lumen, an unusual property that makes it valuable for gastrointestinal inflammation research

Skipping a single weekly dose, including when a provider asks you to hold it before surgery, is generally manageable

As weight management is critical in diabetes care, this benefit aligns with our holistic approach to improving insulin sensitivity and overall health outcomes