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Healio: What are some concerns with SGLT2 inhibitor use during pregnancy
Understanding this difference is important because GLP-1 therapy is not a trend, a cosmetic injection, or a one-size-fits-all solution
Allometric scaling: Using the FDA's standard body surface area conversion (rat dose x 0.162), the human equivalent range is roughly 110-560 mcg/day -- which is where the community's 250-500 mcg/day window comes from
generally well-tolerated Cancer concern: NAD+ supports cellular metabolism including in cancer cells
A milder allergic cough that develops days into treatment but doesn't progress is usually manageable with antihistamines and provider evaluation
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