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A possible clue to their mechanism is provided by a trial with flumazenil (Anexate, Romazicon) a benzodiazepine receptor antagonist, published by Lader and Morton (Journal of Psychopharmacology 1992, 6, 357-63)
Severe side effects are rare but include anaphylaxis (especially in those allergic to cobalt or B)
I often discuss yerba mate's benefits, such as regulating blood sugar, its high antioxidant content, the ways that it can improve digestion, and possible neuroprotective effects
AOD9604 has fewer reported side effects and is better tolerated
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