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[18] Adverse effects [edit] In individuals already taking sulphonylureas, use of DPP-4-class medications concurrently increases their risk for low blood sugar events relative to those on sulphonylureas alone

Product information for GLP-1 receptor agonists includes guidance on recognising pancreatitis symptoms (persistent severe abdominal pain, often radiating to the back, with or without vomiting) and advises discontinuation if acute pancreatitis is suspected

CBS News (2023)

Basal insulin and sulfonylurea/glinide were discontinued at randomisation

L-carnitine may have additional benefits for the dialysis patient: a meta-analysis of 49 clinical trials involving 1734 kidney dialysis patients found a significant decrease in C-reactive protein (a marker of inflammation) and low-density lipoprotein in patients taking carnitine