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With prolonged or high-dose use, receptors may become less responsive, making the peptide less effective
Cephalalgia 39(13):16751682 Noseda R, Kainz V, Borsook D, Burstein R (2014) Neurochemical pathways that converge on thalamic trigeminovascular neurons: potential substrate for modulation of migraine by sleep, food intake, stress and anxiety
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In our study, exogenous GSH enhanced JA signal transduction by inhibiting the expression of JAZ protein-related genes
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