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In vitro, inosine directly inhibits ubiquitin-like modifier-activating enzyme 6 (UBA6), which increases the expression of MHC-I and other genes involved in antigen presentation, thereby enhancing immune recognition 63
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out of the 2.5 billion adults classified as overweight, roughly 890 million met the criteria for obesity, while globally, 43% of the adult population was overweight generally, with 16% being in the obese range
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