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doi:10.1172/JCI110155
Lipopsomal refers to a type of drug or supplement preparation that contains the active drug inside microscopic fat-like particles (called phospholipid bilayers)
In a retrospective study completed by Nadeem et al., it was shown that GLP-1 RAs are associated with an overall fourfold increase in the retention of gastric contents in both diabetic and non-diabetic patients ( p -value 0.8 mL/kg of gastric fluid content (measured from the aspiration/suction canister)
Proposed mechanisms include regulation of endothelial function, influence on blood vessel formation, modulation of inflammatory signaling, and effects on connective tissue-associated processes such as collagen organization
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