Stress Levels: Chronic stress is known to increase oxidative stress, placing a higher demand on the body's antioxidant reserves
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Some people may experience mild digestive upset when first starting supplementation, which typically resolves as the body adjusts
Multiple organ failure including sepsis-induced cardiac dysfunction seem to be the result of numerous factors as overwhelming inflammation and nitric oxide synthesis impairment associated with mitochondrial dysfunction and increased oxidative stress (Cecchini and Cecchini, 2020)