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70 Additionally, lactylation at K91 of transcription factor EB (TFEB) impedes it from interacting with E3 ubiquitin ligase WW domain-containing E3 ubiquitin protein ligase 2 (WWP2), thereby inhibiting TFEB ubiquitination and proteasome degradation and eventually augmenting TFEB activity

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Figure 7 RNA Sequence and Mechanism The mRNA expression profiling was performed among both GSTM3 overexpression and GSTM3 knockdown cells

Glutathione is a free-radical fighter that wears many hats such as: metabolizes nutrients assists with gene expression is part of DNA and protein synthesis fosters cell growth stimulates cell apoptosis (planned cell death, like a cellular housecleaning) produces cytokines (cells that assist with inflammatory and immune responses) Glutathione protects your body by filtering out free radicals and combating oxidative stress in your cells, including toxins like mercury

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