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Lancet 378 , 13061315 (2011)
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Previously, a study based on proteomic analysis had revealed marked transcriptional repression of other Nrf2-induced antioxidant proteins including CK2, ERK1/2, PKC, GPx, Mgst1, peroxiredoxin 3 (Prdx3), in both preclinical models and in human spinal MNs from ALS patients [253]
KPV puts the literal brakes on this inflammatory response
For instance, -tocopherol can protect the physiological properties of lipid bilayer membranes and may influence the activity of membrane proteins and enzymes (5)
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