doi: 10.3389/fmed.2022.875430 Summary Keywords glucagon-like peptide-1 receptor agonist (GLP-1RA), incretin based therapy, glucose-depent insulinotropic peptide (GIP), dual agonists, tirzepatide, type 2 diabetes Citation Gallwitz B (2022) Clinical perspectives on the use of the GIP/GLP-1 receptor agonist tirzepatide for the treatment of type-2 diabetes and obesity
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Due to tirzepatide's long half-life (approximately five days) and delayed peak concentration (8-72 hours after injection), symptoms typically reflect steady-state effects rather than immediate post-injection peaks
These side effects are generally mild to moderate and usually go away within a few weeks
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