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V., Kumaraswamy, E., Gladyshev, V
Conversely, the increased export of 2-Oxoglutarate into the cytosol could augment the activity of Fe (II) 2-oxoglutarate (2OG)dependent oxygenases, enzymes that catalyze a variety of critical reactions including hydroxylation, halogenation, desaturation, and ring transformation
Consequently, the contribution of xCT to cancer cell growth may be overestimated, whereas the importance of GGTs may be undervalued
Further, decreased GSH has been associated with liver disease
Palana, C., Aburumman, A., Kachungunu, C
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