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It is a DPP-4 inhibitor, meaning it works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4)
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The overall conformation of the GHSR-G i complex in our structures highly resembles the canonical state of the NTSR1-G i complex
Due to the overlapping inhibitory profile of CD and Cyto D [65], caveolae, clathrin mediated or macropinocytotic pathways may participate in the 3-PLG uptake in brain endothelial cells
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