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GLP-1 drugs represent a step towards even more effective management of that risk." -Professor Robert Storey, Professor of Cardiology, University of Sheffield, commenting on the NICE guidance, April 2026 What the Trials Have Shown The pivotal trial underpinning the NICE decision is the SELECT study, a large-scale randomised controlled trial examining the cardiovascular outcomes of semaglutide in people with established heart and circulatory disease who are overweight
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The medication has been shown to improve other cardiovascular risk factors, such as lowering blood pressure and improving lipid profiles, thereby further mitigating potential heart-related issues
For tirzepatide users experiencing anxiety, aim for 150 minutes of moderate activity per week, broken into manageable sessions
Keep track of how you feel after consuming protein shakesnote any patterns of nausea, bloating, or discomfort
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