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In addition, there are several other genetic alterations associated with the glutamine dependency of cancer, and these mutations in genes may influence the extent to which tumor cells rely on glutaminase metabolism
Association of IRF5 polymorphisms with susceptibility to macrophage activation syndrome in patients with juvenile idiopathic arthritis
Age-related macular degeneration: role of oxidative stress and blood vessels
Seiler A, Schneider M, Frster H, Roth S, Wirth EK, Culmsee C, et al
These studies suggest that most glutamine-dependent protein translation activities can still proceed under asparagine supplementation in a glutamine-deprived environment, although the exact mechanism is still unknown
