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Intravenous administration is expected to deliver 100% bioavailability of glutathione, much more compared to that achieved by oral administration
This enhances intracellular detoxification capacity and reduces ROS accumulation
169 SIRT1 activates antioxidant transcription factors such as FOXO3a and Nrf2 via deacetylation, 170 upregulating enzymes including superoxide dismutase (SOD) 1/2, GSH-Px, 171 and HO-1
Prevent cancer progression in patients not undergoing chemotherapy
Serum is more widely available
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