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By mimicking the activity of these two incretin hormones, Tirzepatide enhances insulin secretion, suppresses glucagon release, slows gastric emptying, and promotes a sense of satiety
39 However, this study did not control for relevant risk factors such as smoking, blood pressure, and body mass index
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This substantially exceeded both semaglutide (approximately 15%) and tirzepatide (approximately 21%) results from comparable trial durations
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