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When GLP-1 reaches the pancreas, it binds to GLP-1 receptors (GLP-1R) expressed on the pancreatic cells, stimulating insulin release
Supports skin repair and renewal
Secondary endpoints were univariately compared between the GLP-1-RA and UCWM groups
Further, the CVOTs in general also suggested a potential benefit of GLP-1 RAs on HF, positioning GLP-1 RAs as another advanced option alongside SGLT2 inhibitors in the otherwise sparse treatment armamentarium for especially HFpEF
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