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By month 3, gastrointestinal symptoms like nausea and digestive discomfort typically resolve for the majority of users, marking the transition from the adaptation phase into the acceleration phase of weight loss
The effect of semaglutide compared to placebo on estimated GFR was calculated using a MMRM model with two-sided P-values and with fixed effects for treatment, visit, baseline log-transformed UACR, the interaction between treatment and visit, and the interaction between baseline and estimated GFR
Butler, J., Bjurstrom, M., Marceau, A
The STEP 1 trial showed an average weight loss of 14.9% of body weight at 68 weeks
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