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Because these are high-cost drugs, the [documentation requirements] are incredibly high
What is supported in animal models Increased lipolysis, increased fat oxidation, decreased lipogenesis, no apparent effect on plasma glucose or insulin sensitivity, and signal that intact beta-3 adrenergic receptor activity matters for the fat-loss effect
Overuse or inappropriate administration may lead to nutrient imbalances
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It is not FDA-approved for weight loss and is typically sold outside standard prescription channels as a compounded or research product
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