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Finally, we turned to targeting Tsa1, human PRDX3, and human PRDX5 (which are the two 2Cys peroxiredoxins residing in the matrix of human mitochondria) as well as human PRDX6 (a 1Cys peroxiredoxin found in the cytosol of human cells) to the mitochondrial matrix of prx1 cells (Appendix Fig S6A)
Bacteriostatic water for Injection, USP (United States Pharmacopeia) is sterile water containing 0.9% benzyl alcohol as a preservative
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With a pH of 1.5 or less, this acidic fire destroys the peptide bonds in reduced glutathione, disintegrating the molecule before it ever hits the intestines
