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Dungan KM, Povedano ST, Forst T, Gonzlez JGG, Atisso C, Sealls W, et al

For example, exosomal circUSP7 from NSCLC cells inhibits miR-934 in CD8 T cells, upregulates SHP2, suppresses effector cytokine secretion (e.g., TNF-, IFN-), and induces T-cell exhaustion, thereby impairing anti-PD-1 efficacy