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announced that it has submitted an IND application to the FDA for MBX 4291, a long-acting GLP-1/GIP receptor co-agonist prodrug targeting obesity, which received regulatory clearance in July

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The functional consequence in animal models is synergistic rather than additive GH output: GHRH-R priming increases the pool of releasable GH vesicles, and GHS-R1a co-stimulation then drives a larger amplitude pulse than either receptor produces alone

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Plasma proteomics of COVID-19-associated cardiovascular complications: implications for pathophysiology and therapeutics

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