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Um, the, the fear around this came about when we looked at studies involving rats where there was an increase of specifically medullary thyroid carcinoma
The apparent overlap in redox potentials could suggest that the cytosolic glutathione and NADP redox couples are able to rapidly equilibrate with each other, for example through the action of glutathione reductase
The research, published in "Diabetes, Obesity, and Metabolism," illustrated that a variance in dosage or type of drug can impact results
However, one caveat is that most available studies consist largely of normal ejection fraction coronary artery bypass grafts procedures, which reported low rates of inotropic support use in general: 11% in the GLP-1RA and 17% in the control group (Hulst et al
