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Plateau after initial improvement, consider cycling (8 weeks on, 4 weeks off) or adding complementary interventions
The idea that BPC-157 and TB-500 work synergistically is a hypothesis based on their complementary mechanisms in separate studies, not a finding from controlled combination research
This is the most straightforward pathway to reduced effectiveness
However, our data suggest that such inhibitors may have more utility when given in combination with 5FU-based chemotherapy
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