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Prevents continued benefit and requires cycling to restore normal sensitivity
Also, individuals who have undergone certain surgical procedures, including intestinal resection, bypass, or bariatric surgery, which may reduce Vitamin B12 absorption, are also eligible
For men who do not respond to PDE5 inhibitors or have contraindications, these alternatives offer proven benefits
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One study in healthy rat brain mitochondria also did not observe any direct effect of trimetazidine on mitochondrial permeability transition [143]
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