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In research, it functions as a signal peptide associated with collagen synthesis, fibroblast activation, antioxidant signaling, and broad gene modulation
Leaf-sheath tissue of 1015 mm at the feeding site (crown tissue above the root-shoot junction) was cut out, insects removed and used for sample extraction for various analyses
Dig Dis Sci 55: 13961405
One review concluded that vitamin B12 plays a key role in fat metabolism, noting that a deficiency could be linked to increased fat accumulation and obesity ( Another animal study found that severe vitamin B12 deficiency led to a significant increase in body fat percentage and cholesterol levels in pregnant mice ( Whats more, one animal study showed that administering B vitamins to rats fed a high fat diet reduced weight gain and increased levels of several enzymes that influence metabolism, compared with a control group ( However, current evidence is lacking, and additional high quality studies are needed to determine how vitamin B12 may affect metabolism and body fat in humans
Sakaguchi S, Yamaguchi T, Nomura T, Ono M
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